Relevance of suppressor of cytokine signaling proteins (SOCS) for the molecular pathogenesis of colorectal carcinoma.

Study Objective

• Determine if methylated SOCS promotor regions can be used as markers for colon carcinoma.
• Determine if dysregulated feedback inhibition of cytokine/growth factor signalling via SOCS proteins does contribute to the molecular pathogenesis of colorectal carcinoma

Participation conditions

Inclusion criteria:

• Patients with a suspected or confirmed diagnosis of colorectal cancer or scheduled for surgical resection of their primary tumor and / or metastases.

Exclusion criteria:

• Pregnant women
• Minors (subjects less than 18 years of age)
• Prisoners
• Subjects unable to consent

CHL